STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CNBG_5568Phosphoadenosine phosphosulfate reductase. (272 aa)    
Predicted Functional Partners:
CNBG_5344
Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate.
  
 0.994
CNBG_2416
Sulfite reductase (NADPH) flavoprotein alpha-component.
 
 
 0.976
CNBG_4615
Sulfite reductase (NADPH) hemoprotein, beta-component.
 
 
 0.974
MET3
Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family.
  
 
 0.956
CNBG_0234
3'(2'),5'-bisphosphate nucleotidase.
  
 
 0.921
CNBG_4729
Uroporphyrinogen-III C-methyltransferase.
 
  
 0.850
CNBG_0583
NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
  
 
 0.791
CNBG_9673
Uncharacterized protein.
  
 
 0.791
TAH18
NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of DRE2. Positively controls H(2)O(2)-induced cell death; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
  
 
 0.754
CNBG_9382
Riboflavin kinase.
    
 0.753
Your Current Organism:
Cryptococcus gattii
NCBI taxonomy Id: 294750
Other names: C. gattii VGII R265, Cryptococcus bacillisporus R265, Cryptococcus bacillisporus VGII R265, Cryptococcus deuterogattii R265, Cryptococcus gattii R265, Cryptococcus gattii VGII R265, Cryptococcus neoformans R265
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