purB_1 protein (Yersinia frederiksenii) - STRING interaction network

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Score

purB_1

Adenylosuccinate lyase. (458 aa)

Predicted Functional Partners:

purI_1

0.975

purA

0.851

guaA

0.832

purC

0.758

purF

0.742

purD

0.727

purH

0.714

purN

0.709

purI_2

0.695

purK

0.674

Your Current Organism:

Yersinia frederiksenii

NCBI taxonomy Id: 29484
Other names: ATCC 33641, CCUG 11293, CIP 80.29, DSM 18490, NCTC 11470, Y. frederiksenii, strain 6175

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
guaA	purA	ERS008455_01638	ERS008455_02450	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.933
guaA	purB_1	ERS008455_01638	ERS008455_00530	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Adenylosuccinate lyase.	0.832
guaA	purC	ERS008455_01638	ERS008455_01699	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family.	0.668
guaA	purD	ERS008455_01638	ERS008455_03918	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Phosphoribosylamine--glycine ligase; Belongs to the GARS family.	0.884
guaA	purF	ERS008455_01638	ERS008455_01437	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.827
guaA	purH	ERS008455_01638	ERS008455_03917	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.	0.867
guaA	purI_1	ERS008455_01638	ERS008455_01587	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.	0.988
guaA	purI_2	ERS008455_01638	ERS008455_01688	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Phosphoribosylaminoimidazole synthetase.	0.665
guaA	purK	ERS008455_01638	ERS008455_02149	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR); Belongs to the PurK/PurT family.	0.673
guaA	purN	ERS008455_01638	ERS008455_01687	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.	0.526
purA	guaA	ERS008455_02450	ERS008455_01638	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.933
purA	purB_1	ERS008455_02450	ERS008455_00530	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	Adenylosuccinate lyase.	0.851
purA	purC	ERS008455_02450	ERS008455_01699	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family.	0.772
purA	purD	ERS008455_02450	ERS008455_03918	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	Phosphoribosylamine--glycine ligase; Belongs to the GARS family.	0.777
purA	purF	ERS008455_02450	ERS008455_01437	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.638
purA	purH	ERS008455_02450	ERS008455_03917	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.	0.778
purA	purI_1	ERS008455_02450	ERS008455_01587	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.	0.961
purA	purI_2	ERS008455_02450	ERS008455_01688	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	Phosphoribosylaminoimidazole synthetase.	0.579
purA	purK	ERS008455_02450	ERS008455_02149	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR); Belongs to the PurK/PurT family.	0.718
purA	purN	ERS008455_02450	ERS008455_01687	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.	0.571