node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aceE | aceF | ERS008455_00806 | ERS008455_00807 | Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoamide acetyltransferase. | 0.993 |
aceE | lpd_1 | ERS008455_00806 | ERS008455_00808 | Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoamide dehydrogenase. | 0.987 |
aceE | lpd_2 | ERS008455_00806 | ERS008455_04084 | Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoamide dehydrogenase. | 0.438 |
aceE | sth | ERS008455_00806 | ERS008455_04081 | Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.510 |
aceE | sucA | ERS008455_00806 | ERS008455_02320 | Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 2-oxoglutarate dehydrogenase E1 component. | 0.447 |
aceF | aceE | ERS008455_00807 | ERS008455_00806 | Dihydrolipoamide acetyltransferase. | Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.993 |
aceF | gcsH | ERS008455_00807 | ERS008455_01995 | Dihydrolipoamide acetyltransferase. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.893 |
aceF | gor | ERS008455_00807 | ERS008455_03968 | Dihydrolipoamide acetyltransferase. | Glutathione reductase. | 0.914 |
aceF | lpd_1 | ERS008455_00807 | ERS008455_00808 | Dihydrolipoamide acetyltransferase. | Dihydrolipoamide dehydrogenase. | 0.991 |
aceF | lpd_2 | ERS008455_00807 | ERS008455_04084 | Dihydrolipoamide acetyltransferase. | Dihydrolipoamide dehydrogenase. | 0.892 |
aceF | lplA | ERS008455_00807 | ERS008455_00086 | Dihydrolipoamide acetyltransferase. | Lipoate-protein ligase A; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. Belongs to the LplA family. | 0.869 |
aceF | prsA | ERS008455_00807 | ERS008455_00007 | Dihydrolipoamide acetyltransferase. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.861 |
aceF | sth | ERS008455_00807 | ERS008455_04081 | Dihydrolipoamide acetyltransferase. | Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.920 |
aceF | sucA | ERS008455_00807 | ERS008455_02320 | Dihydrolipoamide acetyltransferase. | 2-oxoglutarate dehydrogenase E1 component. | 0.993 |
aceF | sucC | ERS008455_00807 | ERS008455_02318 | Dihydrolipoamide acetyltransferase. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.794 |
gcsH | aceF | ERS008455_01995 | ERS008455_00807 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoamide acetyltransferase. | 0.893 |
gcsH | gor | ERS008455_01995 | ERS008455_03968 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glutathione reductase. | 0.681 |
gcsH | lpd_1 | ERS008455_01995 | ERS008455_00808 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoamide dehydrogenase. | 0.969 |
gcsH | lpd_2 | ERS008455_01995 | ERS008455_04084 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoamide dehydrogenase. | 0.817 |
gcsH | lplA | ERS008455_01995 | ERS008455_00086 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Lipoate-protein ligase A; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. Belongs to the LplA family. | 0.984 |