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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fruK1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (312 aa)    
Predicted Functional Partners:
fruA
PTS system fructose-specific transporter subunit IIBC.
 
 
 0.999
fpr_1
Bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein.
 
  
 0.997
dhaM
Dihydroxyacetone kinase subunit DhaM; Belongs to the PEP-utilizing enzyme family.
 
  
 0.960
fba
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.936
fbp
fructose-1%2C6-bisphosphatase; Belongs to the FBPase class 1 family.
    
 0.918
glpX
Fructose 1%2C6-bisphosphatase II.
     
 0.900
mtlA
PTS system mannitol-specific transporter subunit IICBA.
 
  
 0.859
ptsI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.764
deoR_2
DNA-binding transcriptional repressor DeoR.
 
  
 0.756
lacZ
beta-D-galactosidase; Belongs to the glycosyl hydrolase 2 family.
  
    0.752
Your Current Organism:
Yersinia frederiksenii
NCBI taxonomy Id: 29484
Other names: ATCC 33641, CCUG 11293, CIP 80.29, DSM 18490, NCTC 11470, Y. frederiksenii, strain 6175
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