node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ackA | acs | CH64_1212 | CH64_2908 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.944 |
ackA | maeB | CH64_1212 | CH64_1383 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Malic enzyme, NAD binding domain protein. | 0.908 |
ackA | nifJ | CH64_1212 | CH64_646 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase. | 0.416 |
ackA | poxB | CH64_1212 | CH64_1062 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Thiamine pyrophosphate enzyme, central domain protein; Belongs to the TPP enzyme family. | 0.923 |
acs | ackA | CH64_2908 | CH64_1212 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.944 |
acs | leuA | CH64_2908 | CH64_3273 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.935 |
acs | maeB | CH64_2908 | CH64_1383 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Malic enzyme, NAD binding domain protein. | 0.559 |
acs | nifJ | CH64_2908 | CH64_646 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase. | 0.927 |
acs | poxB | CH64_2908 | CH64_1062 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Thiamine pyrophosphate enzyme, central domain protein; Belongs to the TPP enzyme family. | 0.921 |
ilvN | ilvN-2 | CH64_3277 | CH64_602 | Small subunit; acolac_sm: acetolactate synthase, small subunit. | Acetolactate synthase; Isozyme 1 small subunit. | 0.900 |
ilvN | leuA | CH64_3277 | CH64_3273 | Small subunit; acolac_sm: acetolactate synthase, small subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.973 |
ilvN | leuD | CH64_3277 | CH64_3270 | Small subunit; acolac_sm: acetolactate synthase, small subunit. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.909 |
ilvN | maeA_1 | CH64_3277 | CH64_2959 | Small subunit; acolac_sm: acetolactate synthase, small subunit. | Malic enzyme, NAD binding domain protein. | 0.813 |
ilvN | maeA_2 | CH64_3277 | CH64_32 | Small subunit; acolac_sm: acetolactate synthase, small subunit. | Malic enzyme, NAD binding domain protein. | 0.813 |
ilvN | maeB | CH64_3277 | CH64_1383 | Small subunit; acolac_sm: acetolactate synthase, small subunit. | Malic enzyme, NAD binding domain protein. | 0.844 |
ilvN | nifJ | CH64_3277 | CH64_646 | Small subunit; acolac_sm: acetolactate synthase, small subunit. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase. | 0.913 |
ilvN | poxB | CH64_3277 | CH64_1062 | Small subunit; acolac_sm: acetolactate synthase, small subunit. | Thiamine pyrophosphate enzyme, central domain protein; Belongs to the TPP enzyme family. | 0.978 |
ilvN-2 | ilvN | CH64_602 | CH64_3277 | Acetolactate synthase; Isozyme 1 small subunit. | Small subunit; acolac_sm: acetolactate synthase, small subunit. | 0.900 |
ilvN-2 | leuA | CH64_602 | CH64_3273 | Acetolactate synthase; Isozyme 1 small subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.960 |
ilvN-2 | leuD | CH64_602 | CH64_3270 | Acetolactate synthase; Isozyme 1 small subunit. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.858 |