STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypChypC_hupF: hydrogenase assembly chaperone HypC/HupF. (94 aa)    
Predicted Functional Partners:
hypD
hypD: hydrogenase expression/formation protein HypD; Belongs to the HypD family.
 
 
 0.996
hypE
hypE: hydrogenase expression/formation protein HypE.
 
 
 0.990
hypB
hypB: hydrogenase accessory protein HypB.
 
  
 0.982
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.949
hypF
Carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
 
 0.937
hybC
Hydrogenase-2 large chain; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.915
hybD
hupD: hydrogenase expression/formation protein.
 
  
 0.905
hybO
Hydrogenase-2 small chain.
 
 
 0.890
hybE
Hydrogenase-2 operon protein hybE.
 
  
 0.886
hypA-2
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.817
Your Current Organism:
Yersinia rohdei
NCBI taxonomy Id: 29485
Other names: ATCC 43380, CCUG 38833, CDC 3022-85, CIP 103163, JCM 7376, LMG 8454, LMG:8454, Y. rohdei, strain H271-36/78
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.