Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
flhCFlagellar transcriptional regulator FlhC; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family. (193 aa)    
Predicted Functional Partners:
flhD
Flagellar transcriptional activator family protein; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family.
 
 
 0.999
motA-2
motA1: flagellar motor stator protein MotA.
 
    0.945
motB
Motility protein B.
 
  
 0.929
flgA-2
Flagella basal body P-ring formation protein FlgA; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.
  
  
 0.807
motB_2
Membrane MotB of proton-channel complex MotA/MotB family protein.
  
  
 0.802
cheA
Signal transducing histidine kinase, homodimeric domain protein.
  
  
 0.798
cheW
cheW-like domain protein.
  
  
 0.796
fliL
Flagellar basal body-associated FliL family protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
  
   
 0.793
fliJ-2
Flagellar export protein FliJ; Flagellar protein that affects chemotactic events. Belongs to the FliJ family.
  
   
 0.787
yiaD_3
type_VI_ompA: type VI secretion system peptidoglycan-associated domain.
  
  
 0.746
Your Current Organism:
Yersinia rohdei
NCBI taxonomy Id: 29485
Other names: ATCC 43380, CCUG 38833, CDC 3022-85, CIP 103163, JCM 7376, LMG 8454, LMG:8454, Y. rohdei, strain H271-36/78
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