Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fliD_1Flagellar hook-associated family protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. (466 aa)    
Predicted Functional Partners:
fliS-2
fliS: flagellar protein FliS.
 
 
 0.992
flgL-2
flagell_flgL: flagellar hook-associated protein 3.
 
 
 0.988
flgK-2
flgK_ends: flagellar hook-associated protein FlgK.
 
 
 0.985
fliT
Flagellar protein FliT; Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.
 
 
 0.978
flaA
Flagellin.
 
 
 0.973
flgL
flagell_flgL: flagellar hook-associated protein 3.
 
 
 0.970
flaA-2
Flagellin.
 
 
 0.966
flgE_2
flgEFG_subfam: flagellar hook-basal body family protein.
 
 
 0.964
flgK
flgK_ends: flagellar hook-associated protein FlgK.
 
 
 0.963
flaA-3
Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
 
 
 0.962
Your Current Organism:
Yersinia rohdei
NCBI taxonomy Id: 29485
Other names: ATCC 43380, CCUG 38833, CDC 3022-85, CIP 103163, JCM 7376, LMG 8454, LMG:8454, Y. rohdei, strain H271-36/78
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