Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
hyfBHydrogenase-4 component B. (674 aa)    
Predicted Functional Partners:
hyfG
Nickel-dependent hydrogenase family protein.
 
 
 0.999
hyfC
Hydrogenase-4 component C.
 
 
 0.994
hyfI
NADH ubiquinone oxidoreductase, 20 Kd subunit.
 
 
 0.993
hyfD
NADH-Ubiquinone/plastoquinone (complex I), various chains family protein.
 
 
0.982
hyfF
NADH-Ubiquinone/plastoquinone (complex I), various chains family protein.
 
  
0.962
hyfE
Hydrogenase-4 component E.
 
  
 0.958
nuoL
NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L family protein.
 
 
0.957
hyfJ
Formate hydrogenlyase maturation HycH family protein.
 
  
 0.941
hyfH
4Fe-4S dicluster domain protein.
 
 
 0.937
nuoD
NADH dehydrogenase (quinone), D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.
 
 
 0.910
Your Current Organism:
Yersinia rohdei
NCBI taxonomy Id: 29485
Other names: ATCC 43380, CCUG 38833, CDC 3022-85, CIP 103163, JCM 7376, LMG 8454, LMG:8454, Y. rohdei, strain H271-36/78
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