Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hlyDtype_I_hlyD: type I secretion membrane fusion, HlyD family protein. (464 aa)    
Predicted Functional Partners:
apxIB_2
type_I_sec_HlyB: type I secretion system ATPase family protein.
 
 
 0.990
apxIB_1
type_I_sec_HlyB: type I secretion system ATPase family protein.
 
 
 0.989
lagD
ABC transporter family protein.
 
 
 0.847
ompC
Outer membrane protein C; Belongs to the Gram-negative porin family.
      
 0.817
hlyA
Hemolysin-type calcium-binding repeat family protein.
 
  
 0.803
hasD
type_I_sec_PrtD: type I secretion system ATPase family protein.
 
  
 0.734
cusC
outer_NodT: efflux transporter, outer membrane factor (OMF) lipo, NodT family protein.
 
 
 0.695
tolC
type_I_sec_TolC: type I secretion outer membrane, TolC family protein.
  
 
 0.693
macB_1
ABC transporter family protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
  
 0.648
macB_6
ABC transporter family protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
  
 0.648
Your Current Organism:
Yersinia rohdei
NCBI taxonomy Id: 29485
Other names: ATCC 43380, CCUG 38833, CDC 3022-85, CIP 103163, JCM 7376, LMG 8454, LMG:8454, Y. rohdei, strain H271-36/78
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