STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yukIAcyl-homoserine-lactone synthase; Required for the synthesis of an acyl-HSL autoinducer that binds to YukR and which is involved in the regulation of motility and morphology. (216 aa)    
Predicted Functional Partners:
mtnN
5'-methylthioadenosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/U [...]
     
 0.937
yukR
LuxR family transcriptional regulator; Probable transcriptional activator. Binds to an autoinducer molecule.
  
  
 0.837
AKA40001.1
DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.676
AKA38055.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.639
barA_2
Histidine kinase; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.618
barA_1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.567
AKA37725.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.557
AKA39923.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.543
araB2
Ribulokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.485
rbsB13
LacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.485
Your Current Organism:
Yersinia ruckeri
NCBI taxonomy Id: 29486
Other names: ATCC 29473, CCM 6093, CCUG 14190, CDC 2396-61, CIP 82.80, DSM 18506, JCM 15110, JCM 2429, NCIB 2194, NCIMB 2194, NCTC 12986, Y. ruckeri
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.