Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dcuRResponse regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)    
Predicted Functional Partners:
dcuS
Histidine kinase; C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.998
citA
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.879
dcuB
C4-dicarboxylate transporter; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
     
 0.767
barA_1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.661
bvgS
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.521
dctA_2
C4-dicarboxylate transporter; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
     
 0.517
cimH
Malate permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.497
arcB_2
Aerobic respiration control sensor protein ArcB; Sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.432
kdgR_1
Transcriptional regulator; Regulates the genes involved in 2-keto-3-deoxy gluconate transport and catabolism; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.424
Your Current Organism:
Yersinia ruckeri
NCBI taxonomy Id: 29486
Other names: ATCC 29473, CCM 6093, CCUG 14190, CDC 2396-61, CIP 82.80, DSM 18506, JCM 15110, JCM 2429, NCIB 2194, NCIMB 2194, NCTC 12986, Y. ruckeri
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