node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
acrB | emrA | UGYR_14640 | UGYR_06480 | Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | With ErmA and TolC forms a multidrug efflux system; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.402 |
acrB | macB | UGYR_14640 | UGYR_16380 | Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Macrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.631 |
acrB | pF | UGYR_14640 | UGYR_00510 | Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.669 |
acrB | yhcQ | UGYR_14640 | UGYR_08225 | Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | P-hydroxybenzoic acid efflux subunit AaeA; Forms an efflux pump with AaeB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.471 |
emrA | acrB | UGYR_06480 | UGYR_14640 | With ErmA and TolC forms a multidrug efflux system; Derived by automated computational analysis using gene prediction method: Protein Homology. | Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.402 |
emrA | macB | UGYR_06480 | UGYR_16380 | With ErmA and TolC forms a multidrug efflux system; Derived by automated computational analysis using gene prediction method: Protein Homology. | Macrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.909 |
emrA | pF | UGYR_06480 | UGYR_00510 | With ErmA and TolC forms a multidrug efflux system; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.753 |
hasD_2 | p1 | UGYR_09605 | UGYR_00490 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine 3-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.840 |
hasD_2 | pD | UGYR_09605 | UGYR_00500 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.632 |
hasD_2 | pE | UGYR_09605 | UGYR_00505 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.829 |
hasD_2 | pF | UGYR_09605 | UGYR_00510 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.664 |
hasD_2 | prsE_2 | UGYR_09605 | UGYR_09600 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hemolysin secretion protein D; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.960 |
macA_2 | macB | UGYR_15790 | UGYR_16380 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Macrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.917 |
macA_2 | pF | UGYR_15790 | UGYR_00510 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.703 |
macA_2 | yhcQ | UGYR_15790 | UGYR_08225 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | P-hydroxybenzoic acid efflux subunit AaeA; Forms an efflux pump with AaeB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.415 |
macB | acrB | UGYR_16380 | UGYR_14640 | Macrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.631 |
macB | emrA | UGYR_16380 | UGYR_06480 | Macrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | With ErmA and TolC forms a multidrug efflux system; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.909 |
macB | macA_2 | UGYR_16380 | UGYR_15790 | Macrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.917 |
macB | pE | UGYR_16380 | UGYR_00505 | Macrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.897 |
macB | pF | UGYR_16380 | UGYR_00510 | Macrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.932 |