STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hycAFormate hydrogenlyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (159 aa)    
Predicted Functional Partners:
hycE
Hydrogenase 3 large subunit; Formate hydrogenlyase subunit 5; HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.925
hycD
Hydrogenase 3 membrane subunit; Formate hydrogenlyase subunit 4; HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.651
hyfB
NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.623
hyfI
Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.536
hyfA
Formate hydrogenlyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.524
fdhF
Formate dehydrogenase; Selenocysteine-containing polypeptide; hydrogen linked formate dehydrogenase which catalyzes the oxidation of formate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
  
 0.494
hyfH
Electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.493
hyfJ
Required for the maturation of the formate hydrogenlyase complex; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.480
hypA
Hydrogenase nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
    0.440
hycI
Hydrogenase 3 maturation protease; Involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.428
Your Current Organism:
Yersinia ruckeri
NCBI taxonomy Id: 29486
Other names: ATCC 29473, CCM 6093, CCUG 14190, CDC 2396-61, CIP 82.80, DSM 18506, JCM 15110, JCM 2429, NCIB 2194, NCIMB 2194, NCTC 12986, Y. ruckeri
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.