STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hyfRTranscriptional regulator; Regulates the expression of formate dehydrogenase H and hydrogenase-3 structural genes; Derived by automated computational analysis using gene prediction method: Protein Homology. (708 aa)    
Predicted Functional Partners:
barA_1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.901
arcB_2
Aerobic respiration control sensor protein ArcB; Sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.892
glnF
RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.824
hypB
Hydrogenase nickel incorporation protein HypB; GTP hydrolase involved in nickel liganding into hydrogenases; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.814
dosP
Diguanylate phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.750
hypE
Carbamoyl dehydratase HypE; Hydrogenase isoenzymes formation protein; involved in the formation of the cyanate group of the large subunit of the hydrogenase; catalyzes the formation of thiocyanate from thiocarbamate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.706
gltB
Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.669
fsrB
Dihydropteridine reductase; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily.
     
 0.663
hydN
Effector protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.649
cph2_1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.622
Your Current Organism:
Yersinia ruckeri
NCBI taxonomy Id: 29486
Other names: ATCC 29473, CCM 6093, CCUG 14190, CDC 2396-61, CIP 82.80, DSM 18506, JCM 15110, JCM 2429, NCIB 2194, NCIMB 2194, NCTC 12986, Y. ruckeri
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