STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgpBPhosphatidylglycerophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)    
Predicted Functional Partners:
pgsA
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
 
 0.974
pgpA
Phosphatidylglycerophosphatase; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).
  
 
 0.969
AKA39926.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.945
cls
Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
    
 0.942
b4390
Transcriptional regulator; Catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; catalyzes the formation of nicotinamide mononucleotide from nicotinamide riboside; also has a regulatory function; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.783
aas
acyl-ACP synthetase; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.771
mukB
Cell division protein MukB; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily.
  
     0.761
rplF
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.755
AKA39030.1
Translocation and assembly module TamB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.657
yhcP
P-hydroxybenzoic acid efflux subunit AaeB; Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell; Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
  
     0.646
Your Current Organism:
Yersinia ruckeri
NCBI taxonomy Id: 29486
Other names: ATCC 29473, CCM 6093, CCUG 14190, CDC 2396-61, CIP 82.80, DSM 18506, JCM 15110, JCM 2429, NCIB 2194, NCIMB 2194, NCTC 12986, Y. ruckeri
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