STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
manYPTS mannose transporter subunit IIC; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)    
Predicted Functional Partners:
manX
PTS mannose transporter subunit IIAB; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; subunit IIA transfers a phosphoryl group to subunit IIB; subunit IIB transfers the phosphoryl group to the substrate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
manZ_1
PTS mannose transporter subunit IID; Hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
manZ_2
PTS system N-acetylgalactosamine-specific transporter subunit IID; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IID with IIC forms the translocation channel; involved in N-acetylgalactosamine transport; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.998
levE
PTS system N-acetylgalactosamine-specific transporter subunit IIB; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.954
agaF
PTS mannose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.953
hpr
PTS sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.928
manA
Mannose-6-phosphate isomerase; Catalyzes the formation of of fructose 6-phosphate from mannose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannose-6-phosphate isomerase type 1 family.
    
  0.906
mak
Fructokinase; Catalyzes phosphorylation of fructose; cytosolic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.800
fruA
PTS system fructose-specific transporter subunits IIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.778
yobD
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.583
Your Current Organism:
Yersinia ruckeri
NCBI taxonomy Id: 29486
Other names: ATCC 29473, CCM 6093, CCUG 14190, CDC 2396-61, CIP 82.80, DSM 18506, JCM 15110, JCM 2429, NCIB 2194, NCIMB 2194, NCTC 12986, Y. ruckeri
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.