Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
sirAResponse regulator; In Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)    
Predicted Functional Partners:
barA_2
Histidine kinase; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.995
uvrC
Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
    
 0.961
arcB_1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.891
bvgS
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.890
barA_1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.862
uhpB
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.786
nreB
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
   0.768
arcB_2
Aerobic respiration control sensor protein ArcB; Sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.763
narR
Nitrate/nitrite sensor protein NarX; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.728
phoP_1
Response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.623
Your Current Organism:
Yersinia ruckeri
NCBI taxonomy Id: 29486
Other names: ATCC 29473, CCM 6093, CCUG 14190, CDC 2396-61, CIP 82.80, DSM 18506, JCM 15110, JCM 2429, NCIB 2194, NCIMB 2194, NCTC 12986, Y. ruckeri
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