close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
citAHistidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (528 aa)    
Predicted Functional Partners:
dpiA
Two-component response regulator DpiA; Regulates the expression of citrate fermentation genes; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.998
dcuR
Response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.918
arcB_2
Aerobic respiration control sensor protein ArcB; Sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.634
barA_1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.622
kdgR_1
Transcriptional regulator; Regulates the genes involved in 2-keto-3-deoxy gluconate transport and catabolism; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.527
barA_2
Histidine kinase; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.501
arcB_1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.501
bvgS
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.501
uhpA_2
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.500
pgtB
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.487
Your Current Organism:
Yersinia ruckeri
NCBI taxonomy Id: 29486
Other names: ATCC 29473, CCM 6093, CCUG 14190, CDC 2396-61, CIP 82.80, DSM 18506, JCM 15110, JCM 2429, NCIB 2194, NCIMB 2194, NCTC 12986, Y. ruckeri
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.