Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nreBHistidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (512 aa)    
Predicted Functional Partners:
uhpA_2
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.995
uhpA_1
Response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.814
narL
Nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
   0.780
ysrR
LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
   0.780
rcsB_3
Transcriptional regulator; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
  
 
   0.778
sirA
Response regulator; In Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
   0.768
bvgA
feruloyl-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
   0.745
uhpC_2
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.553
potB
Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.490
AKA37642.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.476
Your Current Organism:
Yersinia ruckeri
NCBI taxonomy Id: 29486
Other names: ATCC 29473, CCM 6093, CCUG 14190, CDC 2396-61, CIP 82.80, DSM 18506, JCM 15110, JCM 2429, NCIB 2194, NCIMB 2194, NCTC 12986, Y. ruckeri
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