| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKA39881.1 | rpmB | UGYR_02595 | UGYR_09895 | Iron-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family. | 50S ribosomal protein L28; Required for 70S ribosome assembly; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL28 family. | 0.644 |
| AKA39881.1 | rpsN | UGYR_02595 | UGYR_11390 | Iron-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family. | 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. | 0.659 |
| AKA39881.1 | yjiA | UGYR_02595 | UGYR_04195 | Iron-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.752 |
| ampM | efp2 | UGYR_06710 | UGYR_04175 | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Elongation factor P; Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the elongation factor P family. | 0.740 |
| ampM | rpmB | UGYR_06710 | UGYR_09895 | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 50S ribosomal protein L28; Required for 70S ribosome assembly; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL28 family. | 0.498 |
| ampM | rpmG | UGYR_06710 | UGYR_09890 | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 50S ribosomal protein L33; In Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.493 |
| ampM | rpsN | UGYR_06710 | UGYR_11390 | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. | 0.977 |
| ampM | yjiA | UGYR_06710 | UGYR_04195 | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.830 |
| appA | efp2 | UGYR_04215 | UGYR_04175 | Antibiotic ABC transporter substrate-binding protein; With YejBEF is involved in resistance to microcin C; Derived by automated computational analysis using gene prediction method: Protein Homology. | Elongation factor P; Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the elongation factor P family. | 0.669 |
| appA | spr | UGYR_04215 | UGYR_04205 | Antibiotic ABC transporter substrate-binding protein; With YejBEF is involved in resistance to microcin C; Derived by automated computational analysis using gene prediction method: Protein Homology. | Membrane protein; Mutational suppressor of prc thermosensitivity; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.717 |
| appA | yeiU | UGYR_04215 | UGYR_04200 | Antibiotic ABC transporter substrate-binding protein; With YejBEF is involved in resistance to microcin C; Derived by automated computational analysis using gene prediction method: Protein Homology. | Membrane protein; Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P); Belongs to the LpxT phosphotransferase family. | 0.660 |
| appA | yjiA | UGYR_04215 | UGYR_04195 | Antibiotic ABC transporter substrate-binding protein; With YejBEF is involved in resistance to microcin C; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.715 |
| dksA | yjiA | UGYR_13390 | UGYR_04195 | RNA polymerase-binding transcription factor; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.698 |
| efp2 | ampM | UGYR_04175 | UGYR_06710 | Elongation factor P; Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the elongation factor P family. | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 0.740 |
| efp2 | appA | UGYR_04175 | UGYR_04215 | Elongation factor P; Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the elongation factor P family. | Antibiotic ABC transporter substrate-binding protein; With YejBEF is involved in resistance to microcin C; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.669 |
| efp2 | rpmB | UGYR_04175 | UGYR_09895 | Elongation factor P; Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the elongation factor P family. | 50S ribosomal protein L28; Required for 70S ribosome assembly; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL28 family. | 0.961 |
| efp2 | rpmG | UGYR_04175 | UGYR_09890 | Elongation factor P; Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the elongation factor P family. | 50S ribosomal protein L33; In Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.930 |
| efp2 | rpsN | UGYR_04175 | UGYR_11390 | Elongation factor P; Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the elongation factor P family. | 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. | 0.919 |
| efp2 | spr | UGYR_04175 | UGYR_04205 | Elongation factor P; Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the elongation factor P family. | Membrane protein; Mutational suppressor of prc thermosensitivity; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.606 |
| efp2 | yjiA | UGYR_04175 | UGYR_04195 | Elongation factor P; Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the elongation factor P family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.693 |