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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfcEPhosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (183 aa)    
Predicted Functional Partners:
yfcD
NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.870
AKA38016.1
Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.840
rdgB
Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.808
mazG
Nucleoside triphosphate hydrolase; Functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.587
ycdZ
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.554
icaB
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.474
ycdX
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PHP family.
 
    0.469
ahpC
Peroxiredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.458
yhjH_2
Diguanylate phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.434
yeiG
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
  
  
 0.414
Your Current Organism:
Yersinia ruckeri
NCBI taxonomy Id: 29486
Other names: ATCC 29473, CCM 6093, CCUG 14190, CDC 2396-61, CIP 82.80, DSM 18506, JCM 15110, JCM 2429, NCIB 2194, NCIMB 2194, NCTC 12986, Y. ruckeri
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