STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
srlEPTS system glucitol/sorbitol-specific transporter subunit IIB; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; subunit IIB transfers the phosphoryl group to the substrate; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)    
Predicted Functional Partners:
srlA
PTS system glucitol/sorbitol-specific transporter subunit IIC; Catalyzes the phosphorylation of incoming sugar substrates along with their translocation across the cell membrane; the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
AKA38231.1
PTS system glucitol/sorbitol-specific transporter subunit IIA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
AKA38232.1
Sorbitol-6-phosphate 2-dehydrogenase; Catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.996
AKA38233.1
Regulator for glucitol utilization; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.963
hpr
PTS sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.901
srlR
Transcriptional regulator; Regulates genes involved in glucitol utilization; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.726
mtlA
PTS system mannitol-specific transporter subunit IICBA; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; subunit IIC forms the translocation channel and contains the specific substrate-binding site; subunit IIA is phosphorylated and transfers the phosphoryl group to the IIB subunit; subunit IIB transfers the phosphoryl group to the substrate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.719
mtlD2
Mannitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.700
AKA38235.1
Arabinose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.471
Your Current Organism:
Yersinia ruckeri
NCBI taxonomy Id: 29486
Other names: ATCC 29473, CCM 6093, CCUG 14190, CDC 2396-61, CIP 82.80, DSM 18506, JCM 15110, JCM 2429, NCIB 2194, NCIMB 2194, NCTC 12986, Y. ruckeri
Server load: low (26%) [HD]