STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKA38232.1Sorbitol-6-phosphate 2-dehydrogenase; Catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)    
Predicted Functional Partners:
srlA
PTS system glucitol/sorbitol-specific transporter subunit IIC; Catalyzes the phosphorylation of incoming sugar substrates along with their translocation across the cell membrane; the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.998
AKA38231.1
PTS system glucitol/sorbitol-specific transporter subunit IIA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.998
srlE
PTS system glucitol/sorbitol-specific transporter subunit IIB; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; subunit IIB transfers the phosphoryl group to the substrate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.997
AKA38233.1
Regulator for glucitol utilization; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.957
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.942
manA
Mannose-6-phosphate isomerase; Catalyzes the formation of of fructose 6-phosphate from mannose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannose-6-phosphate isomerase type 1 family.
   
 
 0.937
mtlD2
Mannitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.936
fbp
Catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FBPase class 1 family.
     
 0.936
mak
Fructokinase; Catalyzes phosphorylation of fructose; cytosolic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.936
nuoD
NADH:ubiquinone oxidoreductase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.
   
 
 0.915
Your Current Organism:
Yersinia ruckeri
NCBI taxonomy Id: 29486
Other names: ATCC 29473, CCM 6093, CCUG 14190, CDC 2396-61, CIP 82.80, DSM 18506, JCM 15110, JCM 2429, NCIB 2194, NCIMB 2194, NCTC 12986, Y. ruckeri
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