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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKA38289.1Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)    
Predicted Functional Partners:
yfbV
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.688
glnE
Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...]
      0.662
yihI
GTPase activator; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.
  
     0.627
vacJ
Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.510
AKA37071.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.505
pspB
Phage shock protein; DNA-binding transcriptional regulator; acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.483
AKA38290.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.448
sixA
Phosphohistidine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.442
ampE
Regulatory protein AmpE; Involved in regulation of beta-lactamase; putative signaling protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.428
syd
Secretion protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family.
  
     0.409
Your Current Organism:
Yersinia ruckeri
NCBI taxonomy Id: 29486
Other names: ATCC 29473, CCM 6093, CCUG 14190, CDC 2396-61, CIP 82.80, DSM 18506, JCM 15110, JCM 2429, NCIB 2194, NCIMB 2194, NCTC 12986, Y. ruckeri
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