STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dmlR_3Transcriptional regulator; For aaeXAB operon; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (303 aa)    
Predicted Functional Partners:
cynR
Transcriptional regulator HdfR; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
  
     0.740
gltR
LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family.
  
     0.722
cysB
LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.707
hexA
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family.
  
     0.685
ftsN
Cell division protein FtsN; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
  
    0.644
cmpR_1
Transcriptional regulator; Activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family.
  
     0.634
mpr
Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S1B family.
  
     0.617
yhcP
P-hydroxybenzoic acid efflux subunit AaeB; Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell; Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
 
     0.581
dsbA
Protein disulfide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.564
phoQ
Sensor protein PhoQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.552
Your Current Organism:
Yersinia ruckeri
NCBI taxonomy Id: 29486
Other names: ATCC 29473, CCM 6093, CCUG 14190, CDC 2396-61, CIP 82.80, DSM 18506, JCM 15110, JCM 2429, NCIB 2194, NCIMB 2194, NCTC 12986, Y. ruckeri
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