| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| fruA | fruK | UGYR_04135 | UGYR_04140 | PTS system fructose-specific transporter subunits IIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | 1-phosphofructokinase; Converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. | 0.999 |
| fruA | fruK_1 | UGYR_04135 | UGYR_07385 | PTS system fructose-specific transporter subunits IIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | 6-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. | 0.999 |
| fruA | glpR | UGYR_04135 | UGYR_10900 | PTS system fructose-specific transporter subunits IIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator; Represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.714 |
| fruK | fruA | UGYR_04140 | UGYR_04135 | 1-phosphofructokinase; Converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. | PTS system fructose-specific transporter subunits IIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| fruK | fruK_1 | UGYR_04140 | UGYR_07385 | 1-phosphofructokinase; Converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. | 6-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. | 0.761 |
| fruK | glpR | UGYR_04140 | UGYR_10900 | 1-phosphofructokinase; Converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. | Transcriptional regulator; Represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.662 |
| fruK_1 | fruA | UGYR_07385 | UGYR_04135 | 6-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. | PTS system fructose-specific transporter subunits IIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| fruK_1 | fruK | UGYR_07385 | UGYR_04140 | 6-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. | 1-phosphofructokinase; Converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. | 0.761 |
| fruK_1 | glpR | UGYR_07385 | UGYR_10900 | 6-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. | Transcriptional regulator; Represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.643 |
| glpD | glpR | UGYR_10895 | UGYR_10900 | Glycerol-3-phosphate dehydrogenase; In Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. | Transcriptional regulator; Represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.734 |
| glpG | glpR | UGYR_10905 | UGYR_10900 | Intramembrane serine protease GlpG; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | Transcriptional regulator; Represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.880 |
| glpR | fruA | UGYR_10900 | UGYR_04135 | Transcriptional regulator; Represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS system fructose-specific transporter subunits IIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.714 |
| glpR | fruK | UGYR_10900 | UGYR_04140 | Transcriptional regulator; Represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. | 1-phosphofructokinase; Converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. | 0.662 |
| glpR | fruK_1 | UGYR_10900 | UGYR_07385 | Transcriptional regulator; Represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. | 6-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. | 0.643 |
| glpR | glpD | UGYR_10900 | UGYR_10895 | Transcriptional regulator; Represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycerol-3-phosphate dehydrogenase; In Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.734 |
| glpR | glpG | UGYR_10900 | UGYR_10905 | Transcriptional regulator; Represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. | Intramembrane serine protease GlpG; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | 0.880 |
| glpR | pdhR | UGYR_10900 | UGYR_13275 | Transcriptional regulator; Represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator PdhR; Activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.436 |
| glpR | yfiQ | UGYR_10900 | UGYR_06505 | Transcriptional regulator; Represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein acetyltransferase; Catalyzes the acetylation of lysine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.758 |
| pdhR | glpR | UGYR_13275 | UGYR_10900 | Transcriptional regulator PdhR; Activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator; Represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.436 |
| yfiQ | glpR | UGYR_06505 | UGYR_10900 | Protein acetyltransferase; Catalyzes the acetylation of lysine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator; Represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.758 |