STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ychNHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (117 aa)    
Predicted Functional Partners:
tusC
Protein TusC; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DsrF/TusC family.
  
 0.949
tusB
Sulfur relay protein TusB; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
  
 
 0.897
tusA
Sulfur transfer protein SirA; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
  
 
 0.789
acrR
Transcriptional regulator; Regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.718
kefA_1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.702
ycdZ
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.608
acrA
Multidrug transporter; With AcrD and TolC forms a transport system involved in resistance to a number of compounds including lipophilic antibiotics; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.494
mdtH
Multidrug resistance protein MdtH; Confers resistance to norfloxacin and enoxacin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.483
acrB
Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.473
tusE
Sulfur transfer protein TusE; Part of a sulfur-relay system.
  
 
 0.466
Your Current Organism:
Yersinia ruckeri
NCBI taxonomy Id: 29486
Other names: ATCC 29473, CCM 6093, CCUG 14190, CDC 2396-61, CIP 82.80, DSM 18506, JCM 15110, JCM 2429, NCIB 2194, NCIMB 2194, NCTC 12986, Y. ruckeri
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