| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| glpG | hflB | UGYR_10905 | UGYR_12025 | Intramembrane serine protease GlpG; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.715 |
| glpG | hflK | UGYR_10905 | UGYR_11765 | Intramembrane serine protease GlpG; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | Cell division protein FtsH; HflC and HflK could encode or regulate a protease. | 0.696 |
| glpG | qmcA | UGYR_10905 | UGYR_14830 | Intramembrane serine protease GlpG; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | Protease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.700 |
| hflB | glpG | UGYR_12025 | UGYR_10905 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Intramembrane serine protease GlpG; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | 0.715 |
| hflB | hflK | UGYR_12025 | UGYR_11765 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Cell division protein FtsH; HflC and HflK could encode or regulate a protease. | 0.983 |
| hflB | nuoD | UGYR_12025 | UGYR_04790 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | NADH:ubiquinone oxidoreductase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | 0.517 |
| hflB | qmcA | UGYR_12025 | UGYR_14830 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Protease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.954 |
| hflB | yhjJ | UGYR_12025 | UGYR_10735 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.784 |
| hflB | yidC | UGYR_12025 | UGYR_10345 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Membrane protein insertase; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.556 |
| hflK | glpG | UGYR_11765 | UGYR_10905 | Cell division protein FtsH; HflC and HflK could encode or regulate a protease. | Intramembrane serine protease GlpG; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | 0.696 |
| hflK | hflB | UGYR_11765 | UGYR_12025 | Cell division protein FtsH; HflC and HflK could encode or regulate a protease. | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.983 |
| hflK | nuoD | UGYR_11765 | UGYR_04790 | Cell division protein FtsH; HflC and HflK could encode or regulate a protease. | NADH:ubiquinone oxidoreductase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | 0.576 |
| hflK | qmcA | UGYR_11765 | UGYR_14830 | Cell division protein FtsH; HflC and HflK could encode or regulate a protease. | Protease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.410 |
| hflK | yhjJ | UGYR_11765 | UGYR_10735 | Cell division protein FtsH; HflC and HflK could encode or regulate a protease. | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.542 |
| hflK | yidC | UGYR_11765 | UGYR_10345 | Cell division protein FtsH; HflC and HflK could encode or regulate a protease. | Membrane protein insertase; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.728 |
| hflK | yqgE | UGYR_11765 | UGYR_07240 | Cell division protein FtsH; HflC and HflK could encode or regulate a protease. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0301 (AlgH) family. | 0.447 |
| mscS | qmcA | UGYR_07165 | UGYR_14830 | Mechanosensitive ion channel protein MscS; Participates in the regulation of osmotic pressure changes within the cel; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.491 |
| nuoD | hflB | UGYR_04790 | UGYR_12025 | NADH:ubiquinone oxidoreductase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.517 |
| nuoD | hflK | UGYR_04790 | UGYR_11765 | NADH:ubiquinone oxidoreductase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | Cell division protein FtsH; HflC and HflK could encode or regulate a protease. | 0.576 |
| nuoD | qmcA | UGYR_04790 | UGYR_14830 | NADH:ubiquinone oxidoreductase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | Protease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.576 |