STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKA39669.1CAAX protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)    
Predicted Functional Partners:
AKA39826.1
Ribosomal protein S12 methylthiotransferase accessory factor YcaO; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.819
AKA39705.1
Suppressor of fused protein (SUFU); Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.664
yhlA
Hemolysin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.600
estP
Autotransporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.583
yhlB
Hemolysin activation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.564
AKA40005.1
Chondroitin lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.550
shlA_1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.539
ruvC
Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
     
 0.536
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
     
 0.512
bdbD
Copper-sensitivity protein C; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.503
Your Current Organism:
Yersinia ruckeri
NCBI taxonomy Id: 29486
Other names: ATCC 29473, CCM 6093, CCUG 14190, CDC 2396-61, CIP 82.80, DSM 18506, JCM 15110, JCM 2429, NCIB 2194, NCIMB 2194, NCTC 12986, Y. ruckeri
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