STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ybhTMembrane protein; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export. (46 aa)    
Predicted Functional Partners:
acrB
Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.837
modE
Transcriptional regulator; Represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.583
kdpF
Potassium-transporting ATPase subunit F; One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.545
acrA
Multidrug transporter; With AcrD and TolC forms a transport system involved in resistance to a number of compounds including lipophilic antibiotics; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
    
 
 0.501
pF
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.471
tolC_2
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.471
rsmB
16S rRNA methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
      
 0.460
sfuC
Amino acid ABC transporter substrate-binding protein; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system.
      
 0.456
fbpC
Ferric transporter ATP-binding subunit; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system.
      
 0.456
modA
Molybdate transporter; With ModCB is involved in the high-affinity transport of molybdate; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.456
Your Current Organism:
Yersinia ruckeri
NCBI taxonomy Id: 29486
Other names: ATCC 29473, CCM 6093, CCUG 14190, CDC 2396-61, CIP 82.80, DSM 18506, JCM 15110, JCM 2429, NCIB 2194, NCIMB 2194, NCTC 12986, Y. ruckeri
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