| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKA38073.1 | lolD | UGYR_06475 | UGYR_00370 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Lipoprotein ABC transporter ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. | 0.412 |
| AKA38073.1 | macA_2 | UGYR_06475 | UGYR_15790 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.733 |
| AKA38073.1 | macB | UGYR_06475 | UGYR_16380 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Macrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.933 |
| hisI | macA_2 | UGYR_16145 | UGYR_15790 | phosphoribosyl-ATP pyrophosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.487 |
| lolD | AKA38073.1 | UGYR_00370 | UGYR_06475 | Lipoprotein ABC transporter ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.412 |
| lolD | macA_2 | UGYR_00370 | UGYR_15790 | Lipoprotein ABC transporter ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.520 |
| lolD | macB | UGYR_00370 | UGYR_16380 | Lipoprotein ABC transporter ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. | Macrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.952 |
| lolD | pF | UGYR_00370 | UGYR_00510 | Lipoprotein ABC transporter ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.407 |
| lolD | tolC_2 | UGYR_00370 | UGYR_07650 | Lipoprotein ABC transporter ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.407 |
| macA_2 | AKA38073.1 | UGYR_15790 | UGYR_06475 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.733 |
| macA_2 | hisI | UGYR_15790 | UGYR_16145 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | phosphoribosyl-ATP pyrophosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | 0.487 |
| macA_2 | lolD | UGYR_15790 | UGYR_00370 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Lipoprotein ABC transporter ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. | 0.520 |
| macA_2 | macB | UGYR_15790 | UGYR_16380 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Macrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.917 |
| macA_2 | pF | UGYR_15790 | UGYR_00510 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.703 |
| macA_2 | rutR | UGYR_15790 | UGYR_15795 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.930 |
| macA_2 | tolC_2 | UGYR_15790 | UGYR_07650 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.703 |
| macA_2 | ybhF | UGYR_15790 | UGYR_15785 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.981 |
| macA_2 | ybhR | UGYR_15790 | UGYR_15775 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.982 |
| macA_2 | ybhS | UGYR_15790 | UGYR_15780 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.983 |
| macB | AKA38073.1 | UGYR_16380 | UGYR_06475 | Macrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.933 |