STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yeiGS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (284 aa)    
Predicted Functional Partners:
frmA
Catalyzes the formation of S-formylglutathione from S-(hydroxymethyl)glutathione; also catalyzes the formation of aldehyde or ketone from alcohols; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 0.999
AKA38786.1
Sulfate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.936
AKA38787.1
Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.936
lip
Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
      0.696
hisC
Histidinol-phosphate aminotransferase; Catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
 
      0.663
gltR
LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family.
       0.487
fadH
2,4-dienoyl-CoA reductase; Catalyzes the formation of trans-2- enoyl-CoA from 2,4-dienoyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.477
adhE
Acetaldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
   
 0.475
ldhA1
Lactate dehydrogenase; Fermentative; catalyzes the formationof pyruvate from lactate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
     
 0.465
tdh
L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.
   
 
 0.447
Your Current Organism:
Yersinia ruckeri
NCBI taxonomy Id: 29486
Other names: ATCC 29473, CCM 6093, CCUG 14190, CDC 2396-61, CIP 82.80, DSM 18506, JCM 15110, JCM 2429, NCIB 2194, NCIMB 2194, NCTC 12986, Y. ruckeri
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