Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ureCUrease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Derived by automated computational analysis using gene prediction method: Protein Homology. (571 aa)    
Predicted Functional Partners:
ureB
Urease subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease beta subunit family.
 0.999
ureA
Urease subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family.
 0.999
ureF
Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 0.997
ureD
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 0.989
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.974
ureE
Urease accessory protein UreE; Involved in the assembly of the urease metallocenter; possible nickel donor; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.962
KGM26604.1
Arginase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.906
KGM27985.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
gltB
Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.543
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
     
 0.504
Your Current Organism:
Photorhabdus luminescens
NCBI taxonomy Id: 29488
Other names: ATCC 29999, CIP 106429, DSM 3368, P. luminescens, Xenorhabdus luminescens, strain Hb
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