node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KGM27557.1 | KGM27570.1 | KS18_13995 | KS18_14065 | Formyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.828 |
KGM27557.1 | KGM27899.1 | KS18_13995 | KS18_10805 | Formyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | dTDP-glucose 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | 0.513 |
KGM27557.1 | KGM27900.1 | KS18_13995 | KS18_10810 | Formyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | 0.592 |
KGM27557.1 | arnA | KS18_13995 | KS18_00885 | Formyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the N-terminal section; belongs to the Fmt family. UDP- L-Ara4N formyltransferase subfamily. | 0.738 |
KGM27557.1 | wecE | KS18_13995 | KS18_10820 | Formyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | TDP-4-oxo-6-deoxy-D-glucose aminotransferase; Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate; Belongs to the DegT/DnrJ/EryC1 family. | 0.829 |
KGM27570.1 | KGM27557.1 | KS18_14065 | KS18_13995 | Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Formyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.828 |
KGM27570.1 | KGM27899.1 | KS18_14065 | KS18_10805 | Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | dTDP-glucose 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | 0.985 |
KGM27570.1 | KGM27900.1 | KS18_14065 | KS18_10810 | Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | 0.987 |
KGM27570.1 | arnA | KS18_14065 | KS18_00885 | Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the N-terminal section; belongs to the Fmt family. UDP- L-Ara4N formyltransferase subfamily. | 0.828 |
KGM27570.1 | wecB | KS18_14065 | KS18_10795 | Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. | 0.824 |
KGM27570.1 | wecE | KS18_14065 | KS18_10820 | Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | TDP-4-oxo-6-deoxy-D-glucose aminotransferase; Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate; Belongs to the DegT/DnrJ/EryC1 family. | 0.864 |
KGM27570.1 | wzxE | KS18_14065 | KS18_10825 | Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | O-antigen translocase; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family. | 0.873 |
KGM27899.1 | KGM27557.1 | KS18_10805 | KS18_13995 | dTDP-glucose 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | Formyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.513 |
KGM27899.1 | KGM27570.1 | KS18_10805 | KS18_14065 | dTDP-glucose 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.985 |
KGM27899.1 | KGM27900.1 | KS18_10805 | KS18_10810 | dTDP-glucose 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | 0.997 |
KGM27899.1 | arnA | KS18_10805 | KS18_00885 | dTDP-glucose 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the N-terminal section; belongs to the Fmt family. UDP- L-Ara4N formyltransferase subfamily. | 0.513 |
KGM27899.1 | wecB | KS18_10805 | KS18_10795 | dTDP-glucose 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | UDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. | 0.906 |
KGM27899.1 | wecD | KS18_10805 | KS18_10815 | dTDP-glucose 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | TDP-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. | 0.798 |
KGM27899.1 | wecE | KS18_10805 | KS18_10820 | dTDP-glucose 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | TDP-4-oxo-6-deoxy-D-glucose aminotransferase; Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate; Belongs to the DegT/DnrJ/EryC1 family. | 0.952 |
KGM27899.1 | wecF | KS18_10805 | KS18_10830 | dTDP-glucose 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | 4-alpha-L-fucosyltransferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. | 0.739 |