Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
murQN-acetylmuramic acid-6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily. (301 aa)    
Predicted Functional Partners:
anmK
anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.
  
 0.999
nagA
N-acetylglucosamine-6-phosphate deacetylase; Catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.996
murP
PTS system N-acetylmuramic acid transporter subunits IIBC; Belongs to PEP-dependent PTS system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; requires crr-encoded enzyme IIA-glucose component; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.989
KGM26655.1
PTS N-acetyl-D-glucosamine transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.969
KGM26812.1
PTS system glucose-specific transporter subunit IIA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.912
KGM29257.1
RpiR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.661
KGM27133.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.643
nagZ
Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
 
  
 0.635
KGM27084.1
PTS system trehalose(maltose)-specific transporter subunits IIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.539
KGM26552.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.493
Your Current Organism:
Photorhabdus luminescens
NCBI taxonomy Id: 29488
Other names: ATCC 29999, CIP 106429, DSM 3368, P. luminescens, Xenorhabdus luminescens, strain Hb
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