STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KMK98723.1Catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; Derived by automated computational analysis using gene prediction method: Protein Homology. (449 aa)    
Predicted Functional Partners:
aceF
Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.969
KMK97698.1
Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.963
KMK98211.1
2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.947
KMK94172.1
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.944
gshB
Catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic GSH synthase family.
  
  
 0.939
KMK94529.1
Glutathione S-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.933
KMK93420.1
Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.924
KMK98478.1
Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutathione peroxidase family.
  
 0.923
KMK91333.1
Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutathione peroxidase family.
  
 0.923
KMK90513.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
 
  
 0.923
Your Current Organism:
Aeromonas enteropelogenes
NCBI taxonomy Id: 29489
Other names: A. enteropelogenes, ATCC 49657 [[Aeromonas trota]], ATCC 49803, Aeromonas sp. LK14, Aeromonas trota, Aeromonas tructi, CCUG 29544 [[Aeromonas trota]], CCUG 30367 [[Aeromonas trota]], CECT 4255 [[Aeromonas trota]], CECT 4487, CIP 103677 [[Aeromonas trota]], CIP 104434, DSM 6394, DSM 7312 [[Aeromonas trota]], JCM 8315 [[Aeromonas trota]], JCM 8355, LMG 12223 [[Aeromonas trota]], LMG 12646, LMG:12223 [[Aeromonas trota]], LMG:12646, strain AH2 [[Aeromonas trota]], strain J11
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