Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KMK98383.1Mannitol operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. (173 aa)    
Predicted Functional Partners:
KMK98385.1
PTS system mannitol-specific transporter subunit IICBA; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; subunit IIC forms the translocation channel and contains the specific substrate-binding site; subunit IIA is phosphorylated and transfers the phosphoryl group to the IIB subunit; subunit IIB transfers the phosphoryl group to the substrate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.868
KMK95479.1
PTS sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.840
mtlD
Mannitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.833
KMK93485.1
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
  0.772
KMK94208.1
Fumarate reductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.
  
  
  0.713
KMK94207.1
Fumarate reductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane; Belongs to the FrdC family.
  
  
  0.708
KMK97582.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0253 family.
  
     0.699
lapA
Membrane protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
  
     0.684
KMK90245.1
PTS galactitol transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.683
KMK90207.1
Condesin subunit F; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
  
     0.670
Your Current Organism:
Aeromonas enteropelogenes
NCBI taxonomy Id: 29489
Other names: A. enteropelogenes, ATCC 49657 [[Aeromonas trota]], ATCC 49803, Aeromonas sp. LK14, Aeromonas trota, Aeromonas tructi, CCUG 29544 [[Aeromonas trota]], CCUG 30367 [[Aeromonas trota]], CECT 4255 [[Aeromonas trota]], CECT 4487, CIP 103677 [[Aeromonas trota]], CIP 104434, DSM 6394, DSM 7312 [[Aeromonas trota]], JCM 8315 [[Aeromonas trota]], JCM 8355, LMG 12223 [[Aeromonas trota]], LMG 12646, LMG:12223 [[Aeromonas trota]], LMG:12646, strain AH2 [[Aeromonas trota]], strain J11
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