STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hybDHydrogenase 2 maturation endopeptidase; Protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)    
Predicted Functional Partners:
KMK98058.1
Hydrogenase 2 large subunit; Involved in hydrogen uptake; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 0.987
KMK98055.1
Hydrogenase 2 small subunit; Involved in hydrogen uptake; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.980
KMK98060.1
Hydrogenase biosynthesis protein HybE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.953
KMK98057.1
HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.929
KMK93291.1
NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.876
KMK98056.1
Hydrogenase 2 protein HybA; Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.863
KMK98071.1
Hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
   
 0.849
hypA
Hydrogenase nickel incorporation protein HybF; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.844
KMK98070.1
Hydrogenase assembly protein HupF; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.837
KMK98066.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.833
Your Current Organism:
Aeromonas enteropelogenes
NCBI taxonomy Id: 29489
Other names: A. enteropelogenes, ATCC 49657 [[Aeromonas trota]], ATCC 49803, Aeromonas sp. LK14, Aeromonas trota, Aeromonas tructi, CCUG 29544 [[Aeromonas trota]], CCUG 30367 [[Aeromonas trota]], CECT 4255 [[Aeromonas trota]], CECT 4487, CIP 103677 [[Aeromonas trota]], CIP 104434, DSM 6394, DSM 7312 [[Aeromonas trota]], JCM 8315 [[Aeromonas trota]], JCM 8355, LMG 12223 [[Aeromonas trota]], LMG 12646, LMG:12223 [[Aeromonas trota]], LMG:12646, strain AH2 [[Aeromonas trota]], strain J11
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