| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KMK94172.1 | KMK97104.1 | VL01_10400 | VL01_06420 | Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.896 |
| KMK94172.1 | KMK97530.1 | VL01_10400 | VL01_05215 | Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | With YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.985 |
| KMK94172.1 | KMK97537.1 | VL01_10400 | VL01_05250 | Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase; Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.412 |
| KMK94172.1 | KMK97538.1 | VL01_10400 | VL01_05255 | Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of pyruvate from 2,3-diaminopropionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.922 |
| KMK94172.1 | KMK98423.1 | VL01_10400 | VL01_00925 | Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.418 |
| KMK94172.1 | ilvH | VL01_10400 | VL01_19705 | Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase 3 regulatory subunit; With IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.955 |
| KMK94172.1 | thrA | VL01_10400 | VL01_08590 | Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate kinase; Multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.418 |
| KMK94172.1 | trpC | VL01_10400 | VL01_08120 | Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Indole-3-glycerol phosphate synthase; Monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. | 0.483 |
| KMK97104.1 | KMK94172.1 | VL01_06420 | VL01_10400 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.896 |
| KMK97104.1 | KMK97530.1 | VL01_06420 | VL01_05215 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | With YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.864 |
| KMK97104.1 | KMK97538.1 | VL01_06420 | VL01_05255 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Catalyzes the formation of pyruvate from 2,3-diaminopropionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.827 |
| KMK97104.1 | KMK98423.1 | VL01_06420 | VL01_00925 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.986 |
| KMK97104.1 | ilvH | VL01_06420 | VL01_19705 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Acetolactate synthase 3 regulatory subunit; With IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.798 |
| KMK97104.1 | thrA | VL01_06420 | VL01_08590 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aspartate kinase; Multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.986 |
| KMK97104.1 | trpC | VL01_06420 | VL01_08120 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Indole-3-glycerol phosphate synthase; Monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. | 0.408 |
| KMK97530.1 | KMK94172.1 | VL01_05215 | VL01_10400 | With YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.985 |
| KMK97530.1 | KMK97104.1 | VL01_05215 | VL01_06420 | With YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.864 |
| KMK97530.1 | KMK97536.1 | VL01_05215 | VL01_05245 | With YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phenylhydantoinase; Catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.985 |
| KMK97530.1 | KMK97537.1 | VL01_05215 | VL01_05250 | With YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase; Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.953 |
| KMK97530.1 | KMK97538.1 | VL01_05215 | VL01_05255 | With YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of pyruvate from 2,3-diaminopropionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.847 |
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