| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KMK92463.1 | KMK96189.1 | VL01_14510 | VL01_07465 | Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Sir2 family NAD-dependent protein deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.797 |
| KMK92511.1 | KMK92776.1 | VL01_14760 | VL01_13695 | RNA polymerase sigma factor RpoE; Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. | RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.572 |
| KMK92511.1 | KMK96189.1 | VL01_14760 | VL01_07465 | RNA polymerase sigma factor RpoE; Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. | Sir2 family NAD-dependent protein deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.403 |
| KMK92511.1 | KMK97551.1 | VL01_14760 | VL01_05320 | RNA polymerase sigma factor RpoE; Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. | Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. | 0.508 |
| KMK92776.1 | KMK92511.1 | VL01_13695 | VL01_14760 | RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA polymerase sigma factor RpoE; Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. | 0.572 |
| KMK92776.1 | KMK96189.1 | VL01_13695 | VL01_07465 | RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sir2 family NAD-dependent protein deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.403 |
| KMK92776.1 | KMK97551.1 | VL01_13695 | VL01_05320 | RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. | 0.660 |
| KMK92885.1 | KMK96189.1 | VL01_14290 | VL01_07465 | RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sir2 family NAD-dependent protein deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.403 |
| KMK94564.1 | KMK96189.1 | VL01_09970 | VL01_07465 | Flagellar biosynthesis protein FliO; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sir2 family NAD-dependent protein deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.462 |
| KMK96188.1 | KMK96189.1 | VL01_07460 | VL01_07465 | Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | Sir2 family NAD-dependent protein deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.497 |
| KMK96189.1 | KMK92463.1 | VL01_07465 | VL01_14510 | Sir2 family NAD-dependent protein deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.797 |
| KMK96189.1 | KMK92511.1 | VL01_07465 | VL01_14760 | Sir2 family NAD-dependent protein deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA polymerase sigma factor RpoE; Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. | 0.403 |
| KMK96189.1 | KMK92776.1 | VL01_07465 | VL01_13695 | Sir2 family NAD-dependent protein deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.403 |
| KMK96189.1 | KMK92885.1 | VL01_07465 | VL01_14290 | Sir2 family NAD-dependent protein deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.403 |
| KMK96189.1 | KMK94564.1 | VL01_07465 | VL01_09970 | Sir2 family NAD-dependent protein deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Flagellar biosynthesis protein FliO; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.462 |
| KMK96189.1 | KMK96188.1 | VL01_07465 | VL01_07460 | Sir2 family NAD-dependent protein deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.497 |
| KMK96189.1 | KMK97551.1 | VL01_07465 | VL01_05320 | Sir2 family NAD-dependent protein deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. | 0.403 |
| KMK96189.1 | KMK97552.1 | VL01_07465 | VL01_05325 | Sir2 family NAD-dependent protein deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.403 |
| KMK96189.1 | nhaA | VL01_07465 | VL01_01360 | Sir2 family NAD-dependent protein deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | pH-dependent sodium/proton antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. | 0.809 |
| KMK97551.1 | KMK92511.1 | VL01_05320 | VL01_14760 | Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. | RNA polymerase sigma factor RpoE; Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. | 0.508 |
