Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
macBMacrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (647 aa)    
Predicted Functional Partners:
KMK95436.1
Hemolysin secretion protein D; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.993
KMK92543.1
Macrolide transporter; With MacA is involved in the export of macrolide; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.984
KMK95438.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.976
KMK92544.1
Hemolysin secretion protein D; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.973
KMK97657.1
Outer membrane-specific lipoprotein transporter subunit LolE; Part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.930
KMK97659.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.930
KMK93312.1
Cell division protein FtsX; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.930
KMK93034.1
Peptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.930
KMK98186.1
Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.912
KMK95410.1
Copper transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
 0.898
Your Current Organism:
Aeromonas enteropelogenes
NCBI taxonomy Id: 29489
Other names: A. enteropelogenes, ATCC 49657 [[Aeromonas trota]], ATCC 49803, Aeromonas sp. LK14, Aeromonas trota, Aeromonas tructi, CCUG 29544 [[Aeromonas trota]], CCUG 30367 [[Aeromonas trota]], CECT 4255 [[Aeromonas trota]], CECT 4487, CIP 103677 [[Aeromonas trota]], CIP 104434, DSM 6394, DSM 7312 [[Aeromonas trota]], JCM 8315 [[Aeromonas trota]], JCM 8355, LMG 12223 [[Aeromonas trota]], LMG 12646, LMG:12223 [[Aeromonas trota]], LMG:12646, strain AH2 [[Aeromonas trota]], strain J11
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