STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
gshBCatalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic GSH synthase family. (317 aa)    
Predicted Functional Partners:
gshA
Glutamate--cysteine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
 
 
 0.977
KMK95490.1
Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.940
KMK98723.1
Catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.939
KMK90277.1
Glutathione S-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.923
KMK97987.1
Aminopeptidase B; Catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.916
KMK97988.1
Aminopeptidase B; Probably plays an important role in intracellular peptide degradation.
   
 
 0.916
KMK90214.1
Peptidase M17; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M17 family.
   
 
 0.916
pepA
Multifunctional aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
   
 
 0.916
KMK96059.1
Glutathione S-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.915
KMK94529.1
Glutathione S-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.912
Your Current Organism:
Aeromonas enteropelogenes
NCBI taxonomy Id: 29489
Other names: A. enteropelogenes, ATCC 49657 [[Aeromonas trota]], ATCC 49803, Aeromonas sp. LK14, Aeromonas trota, Aeromonas tructi, CCUG 29544 [[Aeromonas trota]], CCUG 30367 [[Aeromonas trota]], CECT 4255 [[Aeromonas trota]], CECT 4487, CIP 103677 [[Aeromonas trota]], CIP 104434, DSM 6394, DSM 7312 [[Aeromonas trota]], JCM 8315 [[Aeromonas trota]], JCM 8355, LMG 12223 [[Aeromonas trota]], LMG 12646, LMG:12223 [[Aeromonas trota]], LMG:12646, strain AH2 [[Aeromonas trota]], strain J11
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