| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KMK90455.1 | KMK93432.1 | VL01_19405 | VL01_12535 | Catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Formate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.424 |
| KMK90455.1 | napA | VL01_19405 | VL01_03205 | Catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Nitrate reductase; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. | 0.458 |
| KMK90455.1 | nirD | VL01_19405 | VL01_13740 | Catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.424 |
| KMK90624.1 | KMK93432.1 | VL01_19070 | VL01_12535 | Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | Formate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.759 |
| KMK92719.1 | KMK93432.1 | VL01_13395 | VL01_12535 | Catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Formate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.428 |
| KMK92719.1 | napA | VL01_13395 | VL01_03205 | Catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nitrate reductase; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. | 0.442 |
| KMK92719.1 | nirD | VL01_13395 | VL01_13740 | Catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.424 |
| KMK93432.1 | KMK90455.1 | VL01_12535 | VL01_19405 | Formate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.424 |
| KMK93432.1 | KMK90624.1 | VL01_12535 | VL01_19070 | Formate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | 0.759 |
| KMK93432.1 | KMK92719.1 | VL01_12535 | VL01_13395 | Formate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.428 |
| KMK93432.1 | KMK93433.1 | VL01_12535 | VL01_12540 | Formate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribosomal protein S12 methylthiotransferase accessory factor YcaO; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.440 |
| KMK93432.1 | KMK93496.1 | VL01_12535 | VL01_12530 | Formate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate formate-lyase; Formate acetyltransferase; catalyzes the formation of formate and acetyl-CoA from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.686 |
| KMK93432.1 | cysG | VL01_12535 | VL01_13750 | Formate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.445 |
| KMK93432.1 | cysG-2 | VL01_12535 | VL01_13080 | Formate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.443 |
| KMK93432.1 | napA | VL01_12535 | VL01_03205 | Formate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nitrate reductase; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. | 0.494 |
| KMK93432.1 | nirD | VL01_12535 | VL01_13740 | Formate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.509 |
| KMK93433.1 | KMK93432.1 | VL01_12540 | VL01_12535 | Ribosomal protein S12 methylthiotransferase accessory factor YcaO; Derived by automated computational analysis using gene prediction method: Protein Homology. | Formate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.440 |
| KMK93496.1 | KMK93432.1 | VL01_12530 | VL01_12535 | Pyruvate formate-lyase; Formate acetyltransferase; catalyzes the formation of formate and acetyl-CoA from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Formate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.686 |
| cysG | KMK93432.1 | VL01_13750 | VL01_12535 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Formate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.445 |
| cysG | cysG-2 | VL01_13750 | VL01_13080 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.994 |