| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KMK92147.1 | sfsA | VL01_15725 | VL01_12915 | Adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SfsA family. | 0.873 |
| KMK93008.1 | KMK93009.1 | VL01_12900 | VL01_12905 | Peptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.472 |
| KMK93008.1 | sfsA | VL01_12900 | VL01_12915 | Peptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SfsA family. | 0.432 |
| KMK93009.1 | KMK93008.1 | VL01_12905 | VL01_12900 | ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.472 |
| KMK93009.1 | KMK93010.1 | VL01_12905 | VL01_12910 | ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | 0.553 |
| KMK93009.1 | sfsA | VL01_12905 | VL01_12915 | ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SfsA family. | 0.509 |
| KMK93010.1 | KMK93009.1 | VL01_12910 | VL01_12905 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.553 |
| KMK93010.1 | dksA | VL01_12910 | VL01_12920 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | RNA polymerase-binding transcription factor; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | 0.506 |
| KMK93010.1 | sfsA | VL01_12910 | VL01_12915 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SfsA family. | 0.764 |
| KMK93014.1 | dksA | VL01_12935 | VL01_12920 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA polymerase-binding transcription factor; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | 0.480 |
| KMK93014.1 | gluQ | VL01_12935 | VL01_12925 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | glutamyl-tRNA synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. | 0.606 |
| KMK93014.1 | panB | VL01_12935 | VL01_12940 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.911 |
| KMK93014.1 | pcnB | VL01_12935 | VL01_12930 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | poly(A) polymerase I; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.954 |
| KMK93014.1 | sfsA | VL01_12935 | VL01_12915 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SfsA family. | 0.433 |
| dksA | KMK93010.1 | VL01_12920 | VL01_12910 | RNA polymerase-binding transcription factor; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | 0.506 |
| dksA | KMK93014.1 | VL01_12920 | VL01_12935 | RNA polymerase-binding transcription factor; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.480 |
| dksA | gluQ | VL01_12920 | VL01_12925 | RNA polymerase-binding transcription factor; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | glutamyl-tRNA synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. | 0.675 |
| dksA | panB | VL01_12920 | VL01_12940 | RNA polymerase-binding transcription factor; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.480 |
| dksA | pcnB | VL01_12920 | VL01_12930 | RNA polymerase-binding transcription factor; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | poly(A) polymerase I; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.485 |
| dksA | sfsA | VL01_12920 | VL01_12915 | RNA polymerase-binding transcription factor; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SfsA family. | 0.704 |
