| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KMK92452.1 | KMK97698.1 | VL01_14450 | VL01_04980 | FxsA protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.825 |
| KMK92452.1 | grpE | VL01_14450 | VL01_08425 | FxsA protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.468 |
| KMK92452.1 | hslU | VL01_14450 | VL01_13720 | FxsA protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.603 |
| KMK92452.1 | hslV | VL01_14450 | VL01_13715 | FxsA protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.829 |
| KMK97698.1 | KMK92452.1 | VL01_04980 | VL01_14450 | Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | FxsA protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.825 |
| KMK97698.1 | dnaJ | VL01_04980 | VL01_08415 | Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.816 |
| KMK97698.1 | groEL | VL01_04980 | VL01_14435 | Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.915 |
| KMK97698.1 | groES | VL01_04980 | VL01_14440 | Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.605 |
| KMK97698.1 | grpE | VL01_04980 | VL01_08425 | Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.915 |
| KMK97698.1 | hslU | VL01_04980 | VL01_13720 | Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.917 |
| KMK97698.1 | hslV | VL01_04980 | VL01_13715 | Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.922 |
| KMK97698.1 | htpG | VL01_04980 | VL01_04705 | Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | Heat shock protein 90; Molecular chaperone. Has ATPase activity. | 0.854 |
| KMK97698.1 | lon | VL01_04980 | VL01_05900 | Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-binding protein; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.647 |
| KMK98400.1 | dnaJ | VL01_00800 | VL01_08415 | Ribosome-associated heat shock protein Hsp15; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HSP15 family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.701 |
| KMK98400.1 | groEL | VL01_00800 | VL01_14435 | Ribosome-associated heat shock protein Hsp15; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HSP15 family. | Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.479 |
| KMK98400.1 | grpE | VL01_00800 | VL01_08425 | Ribosome-associated heat shock protein Hsp15; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HSP15 family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.684 |
| KMK98400.1 | hslU | VL01_00800 | VL01_13720 | Ribosome-associated heat shock protein Hsp15; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HSP15 family. | ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.765 |
| KMK98400.1 | hslV | VL01_00800 | VL01_13715 | Ribosome-associated heat shock protein Hsp15; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HSP15 family. | Hypothetical protein; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.816 |
| KMK98400.1 | htpG | VL01_00800 | VL01_04705 | Ribosome-associated heat shock protein Hsp15; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HSP15 family. | Heat shock protein 90; Molecular chaperone. Has ATPase activity. | 0.555 |
| KMK98400.1 | lon | VL01_00800 | VL01_05900 | Ribosome-associated heat shock protein Hsp15; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HSP15 family. | DNA-binding protein; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.440 |
