node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KXF79766.1 | KXF79769.1 | ATN88_12690 | ATN88_12715 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.935 |
KXF79766.1 | KXF82034.1 | ATN88_12690 | ATN88_19655 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.970 |
KXF79766.1 | KXF83406.1 | ATN88_12690 | ATN88_07100 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Molecular chaperone HscC; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the heat shock protein 70 family. | 0.983 |
KXF79766.1 | cyaY | ATN88_12690 | ATN88_20855 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Iron donor protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | 0.996 |
KXF79766.1 | erpA | ATN88_12690 | ATN88_15145 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.897 |
KXF79766.1 | hscB | ATN88_12690 | ATN88_12700 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Cobalamin 5'-phosphate synthase; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.999 |
KXF79766.1 | iscA | ATN88_12690 | ATN88_12695 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Iron-sulfur cluster assembly protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | 0.988 |
KXF79766.1 | iscR | ATN88_12690 | ATN88_12680 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Rrf2 family transcriptional regulator; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | 0.978 |
KXF79766.1 | iscS | ATN88_12690 | ATN88_12685 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.999 |
KXF79766.1 | nfuA | ATN88_12690 | ATN88_14590 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.982 |
KXF79769.1 | KXF79766.1 | ATN88_12715 | ATN88_12690 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.935 |
KXF79769.1 | KXF82034.1 | ATN88_12715 | ATN88_19655 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.591 |
KXF79769.1 | KXF83406.1 | ATN88_12715 | ATN88_07100 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone HscC; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the heat shock protein 70 family. | 0.709 |
KXF79769.1 | cyaY | ATN88_12715 | ATN88_20855 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | Iron donor protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | 0.790 |
KXF79769.1 | erpA | ATN88_12715 | ATN88_15145 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.476 |
KXF79769.1 | hscB | ATN88_12715 | ATN88_12700 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobalamin 5'-phosphate synthase; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.973 |
KXF79769.1 | iscA | ATN88_12715 | ATN88_12695 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | Iron-sulfur cluster assembly protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | 0.804 |
KXF79769.1 | iscR | ATN88_12715 | ATN88_12680 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | Rrf2 family transcriptional regulator; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | 0.424 |
KXF79769.1 | iscS | ATN88_12715 | ATN88_12685 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.910 |
KXF79769.1 | nfuA | ATN88_12715 | ATN88_14590 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.754 |