STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BTO12_11890Unannotated protein. (217 aa)    
Predicted Functional Partners:
hisI
Unannotated protein; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.931
BTO12_21030
Unannotated protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.847
metL
Unannotated protein; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.836
BTO12_20200
Unannotated protein; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.836
trpF
Unannotated protein; Belongs to the TrpC family.
    
 0.818
hisB
Unannotated protein; In the N-terminal section; belongs to the histidinol- phosphatase family.
  
  
 0.791
hisF
Unannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
  
 0.786
hisH
Unannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
  
 0.740
serC
Unannotated protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
 
 0.733
hisA
Unannotated protein.
  
  
 0.717
Your Current Organism:
Vibrio splendidus
NCBI taxonomy Id: 29497
Other names: ATCC 33125, Beneckea splendida, CECT 8714 [[Vibrio hemicentroti]], CIP 102893, DSM 19640, DSM 26178 [[Vibrio hemicentroti]], IFO 15643, KCTC 32085 [[Vibrio hemicentroti]], LMG 19031, LMG 4042, LMG:19031, LMG:4042, NBRC 15643, NCCB 53037, NCIMB 1, Photobacter splendidum, V. splendidus, Vibrio hemicentroti, Vibrio hemicentroti Kim et al. 2013, Vibrio sp. AlyHP32, strain AlyHP32 [[Vibrio hemicentroti]]
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