STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hldDUnannotated protein; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (313 aa)    
Predicted Functional Partners:
rpsS
Unannotated protein; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
  0.973
rpsL
Unannotated protein; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
   
 0.972
rpsN
Unannotated protein; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.
   
  0.972
rpsQ
Unannotated protein; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
 0.971
rpsC
Unannotated protein; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
   
 0.971
rpsH
Unannotated protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
   
 0.969
rpsE
Unannotated protein; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
   
 0.968
rplD
Unannotated protein; Forms part of the polypeptide exit tunnel.
   
 0.967
rpsO
Unannotated protein; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
  
  0.966
rpsB
Unannotated protein; Belongs to the universal ribosomal protein uS2 family.
   
 0.966
Your Current Organism:
Vibrio splendidus
NCBI taxonomy Id: 29497
Other names: ATCC 33125, Beneckea splendida, CECT 8714 [[Vibrio hemicentroti]], CIP 102893, DSM 19640, DSM 26178 [[Vibrio hemicentroti]], IFO 15643, KCTC 32085 [[Vibrio hemicentroti]], LMG 19031, LMG 4042, LMG:19031, LMG:4042, NBRC 15643, NCCB 53037, NCIMB 1, Photobacter splendidum, V. splendidus, Vibrio hemicentroti, Vibrio hemicentroti Kim et al. 2013, Vibrio sp. AlyHP32, strain AlyHP32 [[Vibrio hemicentroti]]
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