Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
epsF_1Type II secretion system protein F. (412 aa)    
Predicted Functional Partners:
epsE_1
Type II secretion system protein E.
 
 
 0.990
epsE_2
Type II secretion system protein E.
 
 0.970
pilE1
Fimbrial protein precursor.
 
    0.905
KRG22123.1
Competence protein A.
 
 
 
 0.897
outO
Type 4 prepilin-like proteins leader peptide-processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
  
 0.893
KRG22124.1
Hypothetical protein.
   
 
 0.852
xcpT
Type II secretion system protein G precursor.
 
    0.844
KRG22125.1
Hypothetical protein.
 
  
 0.839
pilT_3
Twitching mobility protein.
  
   
 0.824
pilT_1
Twitching mobility protein.
 
   
 0.798
Your Current Organism:
Berkiella aquae
NCBI taxonomy Id: 295108
Other names: C. Berkiella aquae, Candidatus Berkiella aquae, Coxiellaceae bacterium HT99, Legionella-like amoebal pathogen HT99
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